Stability of Aspirin

Experiment 4: The Stability of Aspirin Introduction Drugs ar produced in various ways and they are presented in galore(postnominal) forms, they testament undergo chemical decomposition or chemical humiliation in a period of time later on production. This can lead to a substantial lowering of the measuring rod of the therapeutic agent in the dosage form.1 T presentfore, it is important to waiting line up come on the best storage condition for that limited drug, so that the drug can maintain its effect and persona for the semipermanent time, thus maintaining its stableness. That particular length of time is cognize as the shelf-life. Many factors will influence drug perceptual constancy such as the pH and temperature. By understanding the kinetics of the subprogram of the breakdown of drug, the amount of drug fragments in a given(p) time can be predicted. The effect of temperature on the stability of acetylsalicylic irate (aspirin) was being investigated in thi s try. The equation of the reaction of acetylsalicylic acrid is: Acetylsalicylic superman Acetic acid + Salicylic acid The application considered here was the stability of aspirin in solution, and how the rate of decomposition wide-ranging with temperature. From the above equation, acetylsalicylic acid would decompose to acetic acid and salicylic acid under moist condition.

To procure the kinetic data on the stability of drug, a turn step to the fore known as accelerated stability test was taken. The decomposition of the drug was speeded up during the try while retaining the rank rewrite of di fferent formulations.2 Aims UV spectroscopy ! was used in the experiment to obtain a number of kinetic data. Besides gaining serviceable experiences in assaying the equipment, the aims of the experiment were to understand the ways that temperature influenced reaction rate by find out the order of reaction with respect to acetylsalicylic acid; finding out the effect of temperature on the rate invariant; and finding out the activation energy via the Arrhenius equation, which described how rate...If you involve to get a full essay, order it on our website: OrderCustomPaper.com

If you want to get a full essay, visit our page: write my paper